Some philosophers—call them pessimists–think we have reason to avoid deferring to testimony to settle our questions in domains where deep understanding is important. Extant defences of pessimism focus on whether deferring to testimony is ever sufficient for acquiring understanding. But I argue that these defences/articulations of pessimism are unsatisfactory. Even if deference to testimony were always insufficient for acquiring understanding—which seems doubtful—this would not explain why we have reason to avoid deferring in certain domains. Instead, I claim we should think (...) about how and when testimony can disincentivize and discourage agents’ coming to understand. I argue that deferring to testimony to settle a question often results in one having less reason to seek broader understanding and thereby sets one up to (continue to) lack understanding. The incentive pessimist appeals to this phenomenon to explain and defend the basic pessimist thought. (shrink)

Joachim Schulte’s introduction provides a distinctive and masterful account of the full range of Wittgenstein’s thought. It is concise but not compressed, substantive but not overloaded with developmental or technical detail, informed by the latest scholarship but not pedantic. Beginners will find it accessible and seasoned students of Wittgenstein will appreciate it for the illuminating overview it provides.

The autobiography of a medium and investigator of extra-sensory phenomena.--L. F.

Polyclonal antibodies raised against the human erythrocyte nucleoside transporter were used to investigate the distribution of the nucleoside transporters in the placenta. Immunoblots of brush-border membranes isolated from the human syncytiotrophoblast revealed a cross-reactive species that co-migrated with the erythrocyte nucleoside transporter as a broad band of apparent M(r) 55,000. In contrast, no labelling was detected in basal membranes containing a similar number of equilibrative nucleoside transporters as assessed by nitrobenzylthioinosine (NBMPR)-binding. The absence of cross-reactive epitopes in basal membranes and (...) their presence in brush-border membranes was confirmed by confocal immunofluorescence microscopy. The results suggest that at least two isoforms of the NBMPR-sensitive nucleoside transporter are present in the human placenta. The lumenal surfaces of fetal capillaries, small placental vessels and umbilical vein ware also strongly labelled by the antibody, a finding that suggests that the high fetal-placental adenosine uptake previously reported is due to endothelial transporters. (shrink)

Possible distributive justice frameworks for providing health care by general practitioners are discussed. The ethical considerations before and after the recent changes to the British National Health Service are contrasted, with particular emphasis on a possible ethical divide that has been produced between fund-holding and non-fund-holding general practitioners. It is argued that general practitioners in non-fund-holding practices can continue as ethical advocates for their patients and distribute health care within an egalitarian framework. However, those in fund-holding practices may now be (...) seen as interest advocates and may have to practise utilitarian distributive justice. Patient groups may be needed to ensure that these general practitioners are seen to act justly in the distribution of the health care resources for which they are now responsible. (shrink)

This article is an attempt to evaluate the Oregon plan from the perspective of a Scandinavian national health care system. The Nordic welfare states are marked by a strong emphasis on equality. As an example of an egalitarian system we present the Norwegian health care model in part one. In part two, the arguments in favor of a one tier system in Norway are presented and compared to Oregon's two tier system. Although we argue, in part three, that a comparison (...) of the degree of explicitness in the prioritization process shows that Norway has much to learn from Oregon, we do believe that the Norwegian system has some attractive elements that may function as an important corrective. In part four we present the Norwegian Guidelines for priority-setting and discuss the weight assigned to the severity of disease criterion. It is argued that the exclusion of information about the severity of disease partly explains the counterintuitive ranking of treatment-condition pairs in Oregon's initial method based on the principle of health maximization. A normative analysis of the conflicting norms of efficiency and equality of results is called for. The final part of the paper is devoted to the problem of rigidity. Henry J. Aaron has argued that the Oregon system is insensitive to inter-individual variations within each diagnosis-treatment pair. This objection is a severe one, since the system might end up treating patients unfairly on the individual level. To overcome this problem, we suggest a selection rule that should be more capable of dealing with the problem of rigidity. (shrink)

Polyclonal antibodies raised against the human erythrocyte nucleoside transporter were used to investigate the distribution of the nucleoside transporters in the placenta. Immunoblots of brush-border membranes isolated from the human syncytiotrophoblast revealed a cross-reactive species that co-migrated with the erythrocyte nucleoside transporter as a broad band of apparent M(r) 55,000. In contrast, no labelling was detected in basal membranes containing a similar number of equilibrative nucleoside transporters as assessed by nitrobenzylthioinosine (NBMPR)-binding. The absence of cross-reactive epitopes in basal membranes and (...) their presence in brush-border membranes was confirmed by confocal immunofluorescence microscopy. The results suggest that at least two isoforms of the NBMPR-sensitive nucleoside transporter are present in the human placenta. The lumenal surfaces of fetal capillaries, small placental vessels and umbilical vein ware also strongly labelled by the antibody, a finding that suggests that the high fetal-placental adenosine uptake previously reported is due to endothelial transporters. (shrink)

This elegant volume is first of all an anthology of carefully selected Augustinian texts, all freshly translated by the author and grouped thematically under six headings: conversion, person, nature, will, faith, and sight. Each set of readings is followed by a personal essay in which an attempt is made to probe their significance. Together with the two introductory chapters and the conclusion, these essays constitute a short monograph whose aim is to capture the inner dynamism of Augustine’s thought rather than (...) to trace its overall development or uncover its sources. Its method is to involve us in the process by which Augustine sought to clarify the meaning of his own existence and therewith the meaning of human existence as a whole. As such, it calls more for participation than for "expertise" or "detachment". (shrink)

Last year's meetings of the leaders of the party and government with groups of creative artists caused a stir in the field of esthetics, placed in the foreground discussion of questions concerning the theory of the realistic image, and led to an examination of the experience accumulated in the party's struggle for socialist realism. In recent years, as a consequence of the spread of mathematical methods of research into the social sciences and even into creative work, old doubts with respect (...) to the specific significance of the creative image in art have again arisen. For several years now, efforts have been made in esthetics to emphasize, as distinctive features of art, other factors in artistic creativity, more accessible to study by the techniques of the natural sciences. (shrink)

The concept of alienation has taken firm root in the field of esthetics. One cannot say that its content is identical in everything one reads. Nonetheless, employment of this concept is always for the purpose, so to speak, of "clarification." It is often employed on the assumption that its use permits one to make clear whatever may be incomprehensible in the form and content of a work of art. It has become customary to have recourse to the concept of alienation (...) in esthetic analysis of modern foreign works of literature and art. As an example, we may cite the international discussion around the work of Franz Kafka, many participants in which hold that Kafka is a "product of alienation," "a prisoner of alienation," and that his work either expresses "his self-alienation" or involves depiction of the "consequences of alienation.". (shrink)

R. J. O'Connell’s latest book has all the sterling literary qualities of its predecessors, St. Augustine’s Early Theory of Man and St. Augustine’s Confessions: The Odyssey of the Soul. The task in the present case was fraught with new and graver perils; for, although considerations on art abound in Augustine, the subject never receives the full-blown treatment to which modern aesthetic theory has accustomed us. The one possible exception to this rule is the De musica, but even it deals with (...) music as a science rather than as an art and does little to alter the perspective established in the other dialogues. The bulk of the essay traces the evolution of Augustine’s theory of art through the early dialogues, the Confessions, and, in less detailed fashion, the works of his mature period. (shrink)

This slender volume contains a rapid sketch of the development of the notions of conscience and synderesis in medieval thought. Its timeliness is vouched for by the fact that conscience, to which appeal is so often made today, has not been thus far a major theme of modern philosophy. Much of the book's information is quarried from O. Lottin's classic study, Psychologie et morale aux XIIe et XIIIe siècles, whose findings have been restated in terms that are meant to be (...) "psychologically" accessible to the modern mind. The Preface calls attention to the undue neglect of medieval philosophy on the part of twentieth-century thinkers, many of whom still cling to the view that philosophy died with Aristotle and came to life again only with Descartes. It also laments the "party spirit" that once tended to characterize the Neo-Scholastic movement, as well as the one-sided emphasis on Thomas Aquinas within that movement. Potts has accordingly sought to broaden the scope of his inquiry by taking into consideration five widely different authors through whose writings one begins to glimpse the subtlety of the medieval teaching on this important topic: Jerome, who introduced the word "synderesis" into the debate ; Peter Lombard, whose Sentences provided the mandatory point of departure for all subsequent discussions of the subject; Philip the Chancellor, the author of the first medieval treatise on conscience; and, finally, Bonaventure and Thomas Aquinas, two of the writers who contributed most significantly to the further elaboration of the doctrine. By the author's own admission, numerous other theologians, whose names are listed in an appendix, could have been included in the roster or substituted for the ones that are included. The book is divided into two even parts, the first of which presents an analysis of the thought of each of the five theologians mentioned, and the second a selection of representative texts from their works. For the convenience of teachers, a "programme for a medieval-philosophy course on conscience" has been added under Appendix 2. (shrink)

The author of these two complementary essays, neither of which he lived to see in final published form, was one of the most distinguished Jesuit scholars of his generation. Alexander Kojève, whose seminar on Hegel he attended from 1934 to 1939, once remarked that he could have been "easily and by far" France's best Marxist theorist if he had so desired. Partly because of the topical nature of his works, but perhaps even more because of his philosophic depth, he was (...) never read as widely outside of France as are his illustrious confrères, Henri de Lubac and Jean Daniélou. Of the one hundred and twenty-odd items listed in his bibliography only three articles have thus far been translated into English. Yet this impressive literary production could well become one of the landmarks of contemporary French Catholicism. (shrink)

Jung’s Crisis is an ambitious book written from the dogmatic perspective of a firm believer in the redeeming virtue of phenomenology. Like the works of Alfred Schutz and Aron Gurvitsch, on which it often relies, it combines a commitment to phenomenology with a lively interest in social theory. Above all, it claims to be the first treatise systematically to apply the relatively new phenomenological paradigm to the realm of politics. Its undergirding thesis is that philosophical phenomenology is destined to supersede (...) all previous as well as all currently dominant modes of political discourse. Phenomenology is understood throughout not simply as a method, as it is for example in Heidegger’s Being and Time, section 7, but in the Husserlian sense of a complete and rigorous science capable of securing universal assent, of synthesizing theory and practice, and of overcoming the numerous dichotomies that have traditionally plagued the house of philosophy. (shrink)

O'Donovan's gracefully written book is a late but welcome addition to an already large body of literature spawned directly or indirectly by A. Nygren's epoch-making Agape and Eros, the first installment of which appeared in 1930. Most of the ground that it covers is aptly described as a battlefield "on which the smoke still hangs heavy". Interestingly enough, Augustine is the first Latin writer to make extensive use of the expression amor sui or "self-love," which occurs some one-hundred and fifty (...) times throughout his voluminous corpus. Although once accepted virtually without question, his views on this crucial subject have not met with universal approval in our century. Nygren was convinced that Augustine had dealt a lethal blow to the self-denying agape of the Gospel by synthesizing it with the essentially self-regarding eros of Platonic philosophy. Others have since rallied to Augustine's defense, but without always doing full justice to the complexity of his thought. Hence the need for a global assessment of the problem based on a careful scrutiny of the evidence at hand. (shrink)

Quine and others have put many problems to quantified modal logic. Their purpose is to show the logic to be paradoxical or at least very peculiar. Many of these problems center around the interplay between modality, quantification and identity.